Obtenga un marco de datos R con valores combinados de varias tablas MySQL

Esto sería más general, suponiendo que la cantidad de tablas con las que está tratando es variable. También cambia el nombre de las columnas de la forma que querías en la función original:

library(RMySQL)

##  Open database:
mydb = dbConnect(MySQL(), user='root', password='', dbname='DataBase')

##  Create function to get values:
GetVals <- function(TableNames) {
    query <- paste0("SELECT ", Tables[1], ".Chr AS chrom, ", Tables[1], ".start AS site, ")
    query <- paste0(query, paste0(Tables, ".methylation AS ", Tables, collapse=", "))
    query <- paste0(query, " FROM ", Tables[1], paste0(" JOIN ", Tables[-1], " ON ", Tables[1], ".Chr=", Tables[-1], ".Chr AND ", Tables[1], ".start=", Tables[-1], ".start", collapse=""))

  rs <- dbSendQuery(mydb, query)
  data <- fetch(rs, n=-1)
  return(data)
}

Tables <- c("Table1", "Table2", "Table3", "Table4")

my_data <- GetVals(Tables)

Esta es la consulta producida para las Tables variable arriba:

> query
[1] "SELECT Table1.Chr AS chrom, Table1.start AS site, Table1.methylation AS Table1, Table2.methylation AS Table2, Table3.methylation AS Table3, Table4.methylation AS Table4 FROM Table1 JOIN Table2 ON Table1.Chr=Table2.Chr AND Table1.start=Table2.start JOIN Table3 ON Table1.Chr=Table3.Chr AND Table1.start=Table3.start JOIN Table4 ON Table1.Chr=Table4.Chr AND Table1.start=Table4.start"