No puede hacer cálculos con alias. Una forma de hacerlo sería simplemente crear otro alias y ordenarlo.
SELECT columns, count(table2.rev_id) As rev_count, sum(table2.rev_rating) As sum_rev_rating, sum(table2.rev_rating)/count(table2.rev_id) as avg_rev_rating
FROM table1
LEFT JOIN table2
ON table1.dom_id = table2.rev_domain_from
WHERE dom_lastreview != 0 AND rev_status = 1
GROUP BY dom_url
ORDER BY avg_rev_rating DESC
