¿Funcionaría esto? ¿No hay alguna función que lo haga mejor?
echo floor(strtotime('2010-08-11 11:18:28')/(60*15))*60*15*1000;
1281505500000
Wednesday, August 11, 2010 11:15:00 AM
echo floor(strtotime('2010-08-11 11:28:28')/(60*15))*60*15*1000;
1281505500000
Wednesday, August 11, 2010 11:15:00 AM
echo floor(strtotime('2010-08-11 00:00:00')/(60*15))*60*15*1000;
1281465000000
Wednesday, August 11, 2010 12:00:00 AM
echo floor(strtotime('2010-08-11 23:59:59')/(60*15))*60*15*1000;
1281550500000
Wednesday, August 11, 2010 11:45:00 PM