Puede usar declaraciones preparadas -
SET @tables = NULL;
SELECT GROUP_CONCAT('`', table_schema, '`.`', table_name,'`') INTO @tables FROM information_schema.tables
WHERE table_schema = 'myDatabase' AND table_name LIKE BINARY 'del%';
SET @tables = CONCAT('DROP TABLE ', @tables);
PREPARE stmt1 FROM @tables;
EXECUTE stmt1;
DEALLOCATE PREPARE stmt1;
Generará y ejecutará una declaración como esta -
DROP TABLE myDatabase.del1, myDatabase.del2, myDatabase.del3;