Prueba:
/usr/local/mysql/bin/mysqladmin -u root -p shutdown
O:
sudo mysqld stop
O:
sudo /usr/local/mysql/bin/mysqld stop
O:
sudo mysql.server stop
Si instala Launchctl en OSX puedes probar:
Puertos Mac
sudo launchctl unload -w /Library/LaunchDaemons/org.macports.mysql.plist
sudo launchctl load -w /Library/LaunchDaemons/org.macports.mysql.plist
Nota:esto persiste después de reiniciar.
Cerveza casera
launchctl unload -w ~/Library/LaunchAgents/homebrew.mxcl.mysql.plist
launchctl load -w ~/Library/LaunchAgents/homebrew.mxcl.mysql.plist
Instalador binario
sudo /Library/StartupItems/MySQLCOM/MySQLCOM stop
sudo /Library/StartupItems/MySQLCOM/MySQLCOM start
sudo /Library/StartupItems/MySQLCOM/MySQLCOM restart
Lo encontré en:https://stackoverflow.com/a/102094/58768